Anti-aging Properties Assessment
Numerous functional foods and nutraceuticals undergo fortification with distinct bioactive ingredients to enhance their ability to slow the aging process. The efficacy and intrinsic mechanisms of various bioactive components in promoting longevity and healthy aging can exhibit variability. Aprofood is equipped with advanced analytical instruments and other laboratory equipment and has an experienced interdisciplinary team of experts designed to help you comprehensively evaluate the bioactivities of your products in the field of anti-aging.
Fig 1. Functional foods improve bone aging. (Arnold M., et al., 2020)
Common Bioactive Compounds with Anti-aging Properties
It has been found that many kinds of bioactive compounds exhibit functional properties that slow down the aging process, and various plants, animals and microorganisms rich in these compounds can be used as ingredients for functional foods. Here are some common examples.
- Omega-3 Fatty Acids
- Coenzyme Q10 (CoQ10)
Anti-aging Mechanism of Action
Anti-aging mechanisms involve multiple mechanisms at the cellular and molecular levels, such as oxidative stress, inflammation, cellular senescence, etc.
Antioxidant Activity
Antioxidants help to combat oxidative stress which can cause damage to cellular components like proteins and lipids, and slow down cellular aging.
DNA Repair and Protection
Functional foods rich in certain vitamins and minerals can support DNA repair mechanisms, helping to maintain genetic stability and prevent the accumulation of mutations associated with aging.
Mitochondrial Function
Functional foods containing coenzyme Q10 (CoQ10) and certain polyphenols may support the improvement of mitochondrial dysfunction and impaired energy production due to aging.
Collagen Production and Skin Health
Vitamin C, zinc and certain amino acids have a role in supporting collagen synthesis, which is key to maintaining skin elasticity and preventing wrinkles.
Hormone Regulation
Certain phytoestrogens in functional legume-based foods can regulate age-related hormones.
Gut Microbiota Influence
Functional foods containing prebiotics, probiotics and fiber can support a healthy gut microbiome, which in turn affects overall health and may influence the aging process.
Our Service
Aprofood provides scientific research services, including cellular and animal model tests, to evaluate the potential effects of functional foods or bioactive compounds in ameliorating aging-related issues.
What Can We Offer?
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Ingredient Profiling. In-depth analysis of functional food ingredients to identify key bioactive compounds.
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Mechanistic Studies. Uncovering the pathways through which these ingredients exert their anti-aging effects.
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Efficacy Assessments. Conducting a thorough evaluation of the effectiveness of functional food ingredients in alleviating age-related processes.
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Safety Evaluations. Ensuring the long-term safety profile of these ingredients for consumption.
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Formulation Guidance. Offering recommendations for seamlessly incorporating anti-aging ingredients into dietary and nutritional formulations.
Service Process of Anti-aging Properties Assessment
Target Confirmation
In Vitro Testing
Data Analysis & Reporting
Experimental Design
In Vivo Testing
In Vitro Testing Method
- Cell Culture Models. Select appropriate cell lines that mimic the aging process or exhibit relevant markers of aging, such as oxidative stress, DNA damage, cellular senescence, and reduced mitochondrial function.
- Measurement of Biomarkers. Assess various cellular parameters related to aging, such as ROS levels, DNA damage markers, mitochondrial function, cellular senescence markers, and inflammation markers.
In Vivo Testing Method
- Animal Experiment Design. Select appropriate animal models and conduct dose and group design.
- Biomarker Analysis. Assess various parameters associated with aging, including oxidative stress markers, inflammation markers, histopathological changes, gene expression patterns, and protein levels, cognitive function, physical activity, muscle strength, skin health, and lifespan.
Applications of Our Service
We can provide services on a variety of topics related to anti-aging functional food research, including but not limited to the following aspects.
Polyphenols and Aging
Investigating the role of polyphenols in counteracting oxidative stress and inflammation.
Mitochondrial Health
Exploring how functional food ingredients bolster mitochondrial function, a pivotal player in the aging process.
Gut Microbiota Modulation
Understanding the impact of anti-aging ingredients on the gut microbiome and its implications for overall health.
As a specialist in the food industry, CD B ioSciences specializes in the supply of food ingredients and the contract development of new ingredients. We have also launched a range of services covering the wider field of functional food and dietary research. From elucidating molecular mechanisms to evaluating safety, our products meet the complex needs of our clients at the forefront of health science. Please feel free to contact us.
Reference:
- Arnold, M.; et al. Functional Food for Elderly High in Antioxidant and Chicken Eggshell Calcium to Reduce the Risk of Osteoporosis—A Narrative Review. Foods. 2021, 10(3):656.
For Research Use Only.
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