Anti-Cancer Properties Assessment
Bioactive compounds in functional foods don't replace cancer therapies but complement treatments, offering extra health benefits and potentially slowing cancer progression. Aprofood provides scientific services to assess your food ingredients' anti-cancer properties and develop innovative products.
Ingredients with Anti-Cancer Properties
Bioactive compounds in many fruits and vegetables have some preventive effect on cancer, although the underlying mechanisms have not yet been fully investigated.
Fig 1. Food components with anti-cancer properties. (Xia B, et al., 2022)
Anti-cancer Mechanism of Action
Antioxidant Activity
Bioactive compounds with antioxidant properties can neutralize free radicals, reducing oxidative stress and cellular damage, which may contribute to cancer prevention.
Anti-Inflammatory Effects
Chronic inflammation is associated with an increased risk of cancer. Some bioactive compounds help mitigate inflammation, which may aid in cancer prevention.
Apoptosis Induction
Bioactive compounds may induce apoptosis (programmed cell death) in cancer cells, preventing uncontrolled growth.
Inhibition of Angiogenesis
Some compounds can inhibit the formation of new blood vessels that feed cancer tumors, restricting their growth.
Cell Cycle Regulation
Certain bioactive compounds may interfere with the cell cycle of cancer cells, preventing their proliferation.
Our Service
Aprofood can generate reliable and conclusive results using a systematic approach to evaluate the anti-cancer properties and cancer prevention/treatment potential of bioactive compounds or food ingredients, providing invaluable insights for the development of cancer-fighting dietary solutions.
Service Offering
Our anticancer activity assessment services involve the following specific studies and analyses.
Functional Food Analysis Service
Uncover the distinct bioactive compounds and potential anticancer properties inherent in functional food ingredients through a comprehensive analysis.
Dose-Response Evaluation Service
Determine the precise dosage levels requisite for optimal anticancer effects, ensuring the efficacy of functional foods.
Molecular Mechanism Investigation Service
Explore the molecular pathways impacted by functional food ingredients, offering valuable insights into the mechanisms behind their anticancer efficacy.
Bioavailability Studies Service
Investigate the bioavailability of compounds, studying the absorption and distribution dynamics within the body to heighten therapeutic advantages.
In Vitro Studies Service
Conduct in-depth studies to replicate the biological environment to assess the effectiveness of functional food ingredients against cancer cells.
Synergistic Effects Exploration Service
Analyze potential synergies among diverse functional food ingredients, revealing combinations that augment their anticancer effects in an intricate interplay.
Service Process of Anti-cancer Properties Assessment
Anti-cancer Properties Assessment
01 Assessment & Planning
Target Confirmation. Understand the specific aspects that you want to investigate.
Experimental Design. Based on the properties of the ingredient and your desired objectives, we will provide a well-designed experiment, including both in vivo and in vitro assays.
04 Verification Report
Data Analysis. Collect experimental data, statistically analyze the significance of the results, and summarize the anticancer properties of the target ingredients based on the results.
Report Generation. Provide a well-organized report that includes any additional information that supports the research process and conclusions.
02 In Vitro Testing
Cell Viability Assays. Measure the effect of the subjected substance on cancer cell viability and proliferation.
Apoptosis Assays. Determine if the subjected substance induces programmed cell death in cancer cells.
Cell Migration and Invasion Assays. Assess the subjected substance's impact on cancer cell migration and invasion, crucial steps in metastasis.
03 In Vivo Testing
Xenograft and Orthotopic Models. Implant cancer cells into animals to observe tumor growth and evaluate the subjected substance's impact on tumor progression.
Transgenic and Knockout Mouse Models. Use genetically modified mice to study the subjected substance's effects on tumor development and progression in a more complex biological system.
Molecular Analysis. Analyzing gene expression profiling, as well as protein expression and signaling pathways.
Applications of Our Service
Aprofood can provide services related to the study of anticancer properties of functional foods, including but not limited to the following aspects.
Phytochemical Analysis
Analyzing the phytochemistry of functional food ingredients to identify key compounds with anticancer effects and to determine the key factors driving their potential in cancer prevention.
Nutrigenomics
Delve into the intricate interplay between functional food ingredients and gene expression. Decipher the molecular mechanisms through which these compounds exert influence on genetic factors linked to cancer, enhancing our understanding of their nutrigenomic impact.
Metabolomics Profiling
Conduct metabolomics studies to elucidate the impact of functional food ingredients on cellular metabolism. Reveal their intricate role in cancer prevention by comprehensively analyzing metabolic profiles.
Immunomodulation Effects
Assess the immunomodulatory properties inherent in functional food ingredients. Reveal their capacity to augment the body's innate defense mechanisms against cancer, providing insights into their potential immunomodulation effects.
As an expert in the field of the food industry, Aprofood specializes in food ingredient supply as well as contract development of new ingredients. No matter what size of your business and where you're located, we'd like to work with you. Please feel free to contact us.
Reference:
- Xia, B.; et al. Cancer prevention effects of foods, food groups, nutrients, and their underlying mechanisms. Food Science & Technology, 2022, 2(3): 437-454.
For Research Use Only.
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