Diosmetin

Product Type:

Plant Extracts

CAS Number:

520-34-3

Cat. Number:

FFH0126

Introduction

Diosmetin is a flavonoid compound that appears as a yellow powder. It is extracted from lemon and also found in various other natural plants, including spearmint and spider incense. Diosmetin is slightly soluble in methanol but readily dissolves in DMSO.

Application

Diosmetin (Diosmin EP Impurity F) is a metabolite of Apigenin. It exhibits anticancer, antimicrobial, antioxidant, oestrogenic, and anti-inflamatory activities.

Product Information

Image
Product Packaging	0.5-5kg/ bag
Synonyms	3', 5, 7-TRIHYDROXY-4'METHOXYFLAVONE; 4'-METHOXY-5, 7, 3'-TRIHYDROXYFLAVONE; 4-METHOXY-5, 7, 3'-TRIHYDROXYFLAVONE
EINECS	208-291-8
Content Specification	98%(HPLC)
Molecular Formula	C16H12O6
Formula Weight	300.26
Melting Point	256-258°C
Boiling Point	576.7±50.0°C(Predicted)
Density	1.512±0.06 g/cm3(Predicted)
Form	Solid
Color	Light Yellow to Yellow
Solubility	Soluble in acetonitrile, DMSO (60 mg/ml), and ethanol (17 mg/ml), clear, light yellow to yellow.
Water Solubility	19 μg/L at 20°C
Vapor Pressure	0Pa at 20°C
pKa	6.50±0.40(Predicted)
Detection method	HPLC
BRN	294492
InChIKey	MBNGWHIJMBWFHU-UHFFFAOYSA-N
LogP	3.1 at 20°C
Hazard Codes	Xi, Xn
Risk Statements	22
Safety Statements	24/25
WGK Germany	3
HS Code	29329990
Definition	ChEBI: Diosmetin is a monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. It has a role as an antioxidant, an antineoplastic agent, a plant metabolite, a tropomyosin-related kinase B receptor agonist, an apoptosis inducer, an angiogenesis inhibitor, a cardioprotective agent, a bone density conservation agent, an anti-inflammatory agent and a vasodilator agent. It is a monomethoxyflavone, a trihydroxyflavone and a 3'-hydroxyflavonoid. It is functionally related to a luteolin. It is a conjugate acid of a diosmetin-7-olate.
Storage	Sealed in dry, 2-8°C

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