Promoting Cardiovascular Health Properties Assessment
In recent years, researchers have focused on the study of bioactive ingredients and the development of functional foods, dietary supplements, and other products specifically designed to help prevent or control cardiovascular disease. Aprofood has a well-established scientific and technical system, along with a team of experts, to support the evaluation of your products' bioactivity in promoting cardiovascular health.
Ingredients with Cardiovascular Health-promoting Properties
Various food ingredients originating from plant, animal or microbial origin are rich in bioactive compounds with cardiovascular health-promoting properties, some examples are the following categories.
- Omega-3 fatty acids. Sources: fatty fish (e.g., salmon, mackerel) and certain plant sources (e.g., flaxseeds, walnuts).
- Polyphenols. Sources: berries, tea, cocoa, and red wine, etc.
- Dietary Fiber. Sources: whole grains, fruits, vegetables, and legumes, etc.
- Sterols and Stanols. Sources: nuts, seeds, and vegetable oils, etc.
- Coenzyme Q10. Sources: meat, fish, and whole grains.
- Lycopene. Sources: tomatoes and other red and pink fruits, etc.
- Magnesium. Sources: tomatoes and other red and pink fruits, etc.
- Resveratrol. Sources: red wine, grapes, and berries, etc.
Fig 1. Protective effects of functional foods against common cardiovascular diseases. (Zuraini NZA, et al.,2021)
Mechanisms of Action for Cardiovascular Health-promoting
The promotion of cardiovascular health by bioactive compounds involves various multiple mechanisms.
Antioxidant and Anti-Inflammatory Effects
Antioxidants help reduce oxidative stress and prevent damage to cells and blood vessels. Anti-inflammatory compounds can reduce chronic inflammation that contributes to atherosclerosis and other cardiovascular diseases.
Endothelial Function Improvement
Nitric oxide (NO)-boosting agents found in foods like beets and leafy greens, can improve endothelial function, leading to better blood vessel dilation and overall cardiovascular health.
Blood Pressure Regulation
Certain bioactive compounds found in garlic and hibiscus can help relax blood vessels and reduce blood pressure, lowering the risk of hypertension and related cardiovascular events.
Lipid Profile Modulation
Influencing lipid metabolism, promoting the reduction of LDL cholesterol levels and increasing HDL cholesterol levels.
Antiplatelet and Antithrombotic Effects
Omega-3 fatty acids and certain polyphenols, have antiplatelet and antithrombotic properties, reducing the risk of blood clot formation and related cardiovascular events.
Improvement in Insulin Sensitivity
Certain bioactive compounds found in cinnamon and turmeric can improve insulin sensitivity and glucose metabolism, reducing the risk of diabetes-related cardiovascular complications.
Our Service
Aprofood provides scientific methods involving in vitro and in vivo testing to evaluate the potential effects of functional foods or bioactive compounds on lipid metabolism, vascular function and blood pressure regulation in animals.
Service Process of Promoting Cardiovascular Health Properties Assessment
Promoting Cardiovascular Health Properties Assessment
01 Assessment & Planning
Target Confirmation. Understand the specific aspects that you want to investigate.
Experimental Design. Based on the properties of the ingredient and your desired objectives, we will provide a well-designed experiment, including both in vivo and in vitro assays.
04 Verification Report
Data Analysis. Analyze the results to evaluate the cardiovascular health-promoting properties of the subject substances.
Report Generation. Provide a detailed report, including study design, methods and conclusions, discussing the potential benefits of the substances in promoting cardiovascular health.
02 In Vitro Testing
Cell Culture Models. Researchers use cultured cells, often endothelial cells or cardiac cells, to study the cellular effects of bioactive compounds. This involves treating the cells with the compound and assessing changes in gene expression, protein levels, oxidative stress, inflammation, and other relevant factors.
03 In Vivo Testing
Animal Model Selection. Select appropriate animal models and design dose and group.
Biomarker Analysis. Analyze blood for various biomarkers related to inflammation, oxidative stress, lipid metabolism, endothelial function, and more. Analyze tissues like heart and blood vessels to observe changes in morphology, cellular markers, and other indicators of cardiovascular health.
Our Advantage
Complete Service Cycle
Our structured approach covers a literature review, experimental design, detailed data collection, meticulous analysis, and a comprehensive final report.
Leading Technology
Using cutting-edge technologies and advanced tools, ensuring precise measurements and analysis, providing clients a competitive advantage.
Consultative Expertise
Experience continuous expert guidance across the service cycle, ensuring a collaborative and insightful research experience.
Confidential Data Management
We prioritize your data's confidentiality, employing stringent security measures to safeguard sensitive information during the research process.
As a specialist in the food industry, Aprofood specializes in the supply of food ingredients and the contract development of new ingredients. We have also launched a range of services covering the wider field of functional food and dietary research. From elucidating molecular mechanisms to evaluating safety, our products meet the complex needs of our clients at the forefront of health science. Please feel free to contact us.
Reference:
- Zuraini, NZA.; et al. Promising Nutritional Fruits Against Cardiovascular Diseases: An Overview of Experimental Evidence and Understanding Their Mechanisms of Action. Vasc Health Risk Manag. 2021, 17:739-769.
For Research Use Only.
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